Immunogen sequence: YDPEAASAPG SGNPCHEASA AQKENAGEDP GLARQAPKPR KQRSSLLEKG LDGAKKAVGG LGKLGKDAVE DLESVGKGAV HDVKDVLDSV L; Positive Samples: Mouse skin
Activin, a disulfide-linked homodimeric protein is secreted by Sertoli cells in the testis and granulosa cells in the ovary. Activins and inhibins are members of the TGF-beta superfamily due to amino acid homology with respect to the conservation of 7 of the 9 cysteine residues common to all TGF-beta forms. To date, seven type I and five type II activin receptors have been cloned from mammals, including activin receptor IA, activin receptor IIA, activin receptor IB, and activin receptor IIB. In addition, two splice variants of activin receptor IIA and five splice variants of activin receptor IIB have been reported.
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Protein Aliases: DCD-1; Dermcidin; diffusible survival/evasion peptide; Preproteolysin; proteolysis inducing factor; survival promoting peptide; Survival-promoting peptide
Gene Aliases: AIDD; DCD; DCD-1; DSEP; HCAP; PIF
UniProt ID: (Human) P81605
Entrez Gene ID: (Human) 117159