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Invitrogen
DCD Polyclonal Antibody
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FIGURE: 1 / 2
DCD Antibody (PA5-96623) in WB
Western blot analysis of DCD in 293T cells. Samples were incubated with DCD Polyclonal antibody (Product # PA5-96623) using a dilution of 1:8,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-96623
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein (or fragment)
Conjugate
Form
Liquid
Concentration
2.7 mg/mL
Amount
270 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: YDPEAASAPG SGNPCHEASA AQKENAGEDP GLARQAPKPR KQRSSLLEKG LDGAKKAVGG LGKLGKDAVE DLESVGKGAV HDVKDVLDSV L; Positive Samples: Mouse skin
Target Information
DCD is a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Dermcidin; diffusible survival/evasion peptide; Preproteolysin; proteolysis inducing factor; secretory protein; survival promoting peptide
Gene Aliases: AIDD; DCD; DCD-1; DSEP; HCAP; PIF
UniProt ID: (Human) P81605
Entrez Gene ID: (Human) 117159
proteolysis
inorganic anion transport
killing of cells of other organism
ion transmembrane transport
defense response to bacterium
defense response to Gram-negative bacterium
defense response to Gram-positive bacterium
defense response to fungus
killing by host of symbiont cells
antimicrobial humoral immune response mediated by antimicrobial peptide
anion transmembrane transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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