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          • Primary Antibodies ›
          • DCK Antibodies

          Fabgennix

          DCK Polyclonal Antibody, FITC

          View all (34) DCK antibodies

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          Cite DCK Polyclonal Antibody, FITC

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          DCK Polyclonal Antibody, FITC

          Product Details

          DCK-Y-FITC

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          -

          Immunohistochemistry (IHC)

          1:50-1:250
          -

          ELISA (ELISA)

          1:10,000
          -

          Immunoprecipitation (IP)

          1:50-1:250
          -
          Product Specifications

          Species Reactivity

          Mouse

          Host/Isotype

          Chicken / IgY

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide taken within amino acid region 210-260 on mouse Deoxycytidine kinase.
          View immunogen

          Conjugate

          FITC FITC FITC

          Excitation/Emission Max

          498/517 nm View spectra spectra

          Form

          Liquid

          Concentration

          0.5-1.5 mg/mL

          Purification

          Affinity chromatography

          Storage buffer

          proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C, store in dark

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: dCK; Deoxyadenosine kinase; Deoxycytidine kinase; Deoxyguanosine kinase

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          Gene Aliases: Dck

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          UniProt ID: (Mouse) P43346

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          Entrez Gene ID: (Mouse) 13178

          View more View less

          Function(s)
          nucleotide binding magnesium ion binding deoxycytidine kinase activity ATP binding drug binding kinase activity transferase activity nucleoside kinase activity pyrimidine deoxyribonucleoside binding protein homodimerization activity nucleotide kinase
          Process(es)
          nucleobase-containing compound metabolic process pyrimidine nucleotide metabolic process deoxyribonucleoside monophosphate biosynthetic process nucleotide biosynthetic process phosphorylation drug metabolic process deoxycytidine metabolic process
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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