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Proteintech
DCT Polyclonal Antibody
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Product Details
13095-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DCT Fusion Protein Ag3714 (1-350 aa encoded by BC028311)
Conjugate
Form
Liquid
Concentration
0.17 mg/mL
Amount
25.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSPLWWGFL LSCLGCKILP GAQGQFPRVC MTVDSLVNKE CCPRLGAESA NVCGSQQGRG QCTEVRADTR PWSGPYILRN QDDRELWPRK FFHRTCKCTG NFAGYNCGDC KFGWTGPNCE RKKPPVIRQN IHSLSPQERE QFLGALDLAK KRVHPDYVIT TQHWLGLLGP NGTQPQFANC SVYDFFVWLH YYSVRDTLLG PGRPYRAIDF SHQGPAFVTW HRYHLLCLER DLQRLIGNES FALPYWNFAT GRNECDVCTD QLFGAARPDD PTLISRNSRF SSWETVCDSL DDYNHLVTLC NGTYEGLLRR NQMGRNSMKL PTLKDIRDCL SLQKFDNPPF FQNSTFSFRN A (1-350 aa encoded by BC028311)
Target Information
The TYR-related proteins, TRP1 and TRP2, are also specifically expressed in melanocytes, and they likewise contribute to the synthesis of melanin within the melanosomes. The TRPs, including TYR, all share a similar transmembrane region, contain two metal-binding regions and a cysteinerich epidermal growth factor motif, and are localized in the melanosomal membrane. These proteins, however, have distinct catalytic activity, and they individually contribute to the biosynthesis of melanin biopolymers. The TRPs are believed to exist as a multi-enzyme complex, as these proteins form aggregates together, and the expression of TRP1 also helps stabilize TYR in melanocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: DCT; DOPAchrome conversion factor; dopachrome delta-isomerase; DOPAchrome isomerase; DOPAchrome oxidoreductase; dopachrome tautomerase; dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2); DT; L-dopachrome Delta-isomerase; L-dopachrome isomerase; L-dopachrome tautomerase; SLATY locus protein; TRP-2; TRP2; tyrosinase related protein-2; Tyrosinase-related protein 2; tyrosinase-related protein-2; tyrosine-related protein 2; unnamed protein product
Gene Aliases: DCT; DT; OCA8; RGD1564975; slaty; slt; TRP-2; TRP2; Tyrp-2; TYRP2
UniProt ID: (Human) P40126, (Mouse) P29812
Entrez Gene ID: (Human) 1638, (Rat) 290484, (Mouse) 13190
positive regulation of neuroblast proliferation
melanin biosynthetic process from tyrosine
neuroblast proliferation
epidermis development
response to blue light
ventricular zone neuroblast division
melanin biosynthetic process
pigmentation
developmental pigmentation
cell development
metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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