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This gene encodes a subunit of dynactin, a component of the cytoplasmic dynein motor machinery involved in minus-end-directed transport. The encoded protein is a component of the pointed-end subcomplex and is thought to bind membranous cargo. A pseudogene of this gene is located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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Protein Aliases: dynactin 4; dynactin 5 (p25); Dynactin subunit 5; Dynactin subunit p25; p25 dynactin subunit
Gene Aliases: 4930427E12Rik; b2b315Clo; C78178; DCTN5; RGD1305654
UniProt ID: (Human) Q9BTE1, (Mouse) Q9QZB9
Entrez Gene ID: (Human) 84516, (Mouse) 59288, (Rat) 308961
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