The protein encoded by this gene acts as a homotetramer to catalyze diacetyl reductase and L-xylulose reductase reactions. The encoded protein may play a role in the uronate cycle of glucose metabolism and in the cellular osmoregulation in the proximal renal tubules. Defects in this gene are a cause of pentosuria. Two transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: carbonyl reductase 2; Carbonyl reductase II; DCR; Dicarbonyl/L-xylulose reductase; HCR2; HCRII; KIDCR; Kidney dicarbonyl reductase; L-xylulose reductase; member 1; P34H; SDR20C1; short chain dehydrogenase/reductase family 20C; Short chain dehydrogenase/reductase family 20C member 1; short chain dehydrogenase/reductase family 20C, member 1; Sperm surface protein P34H; XR
Gene Aliases: DCR; DCXR; HCR2; HCRII; KIDCR; P34H; PNTSU; SDR20C1; XR
UniProt ID: (Human) Q7Z4W1
Entrez Gene ID: (Human) 51181