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Proteintech
DDRGK1 Polyclonal Antibody
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Product Details
21445-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Goat,
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DDRGK1 Fusion Protein Ag13742 (1-314 aa encoded by BC000643)
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
21445-1-AP is a rabbit polyclonal antibody raised against the full-length of human DDRGK1.
Immunogen sequence: MVAPVWYLV AAALLVGFIL FLTRSRGRAA SAGQEPLHNE ELAGAGRVAQ PGPLEPEEPR AGGRPRRRRD LGSRLQAQRR AQRVAWAEAD ENEEEAVILA QEEEGVEKPA ETHLSGKIGA KKLRKLEEKQ ARKAQREAEE AEREERKRLE SQREAEWKKE EERLRLEEEQ KEEEERKARE EQAQREHEEY LKLKEAFVVE EEGVGETMTE EQSQSFLTEF INYIKQSKVV LLEDLASQVG LRTQDTINRI QDLLAEGTIT GVIDDRGKFI YITPEELAAV ANFIRQRGRV SIAELAQASN SLIAWGRESP AQAPA (1-314 aa encoded by BC000643)
Target Information
Protein which interacts with the E3 UFM1-protein ligase UFL1 and one of its substrates TRIP4 and is required for TRIP4 ufmylation. Through TRIP4 ufmylation may regulate nuclear receptors-mediated transcription. May play a role in NF-kappa-B-mediated transcription through regulation of the phosphorylation and the degradation of NFKBIA, the inhibitor of NF-kappa-B. May also play a role in the cellular response to endoplasmic reticulum stress.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Dashurin; DDRGK domain-containing protein 1; UFM1-binding and PCI domain-containing protein 1; UFM1-binding protein 1 containing a PCI domain
Gene Aliases: 1110001I20Rik; 2600009E05Rik; AI326138; C20orf116; DDRGK1; dJ1187M17.3; UFBP1
UniProt ID: (Human) Q96HY6, (Mouse) Q80WW9
Entrez Gene ID: (Human) 65992, (Mouse) 77006
regulation of intracellular estrogen receptor signaling pathway
response to endoplasmic reticulum stress
positive regulation of NF-kappaB transcription factor activity
positive regulation of proteasomal protein catabolic process
positive regulation of I-kappaB phosphorylation
protein K69-linked ufmylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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