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Bioss
DDRGK1 Polyclonal Antibody
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Product Details
BS-8252R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human DDRGK1, amino acids 81-180.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Protein which interacts with the E3 UFM1-protein ligase UFL1 and one of its substrates TRIP4 and is required for TRIP4 ufmylation. Through TRIP4 ufmylation may regulate nuclear receptors-mediated transcription. May play a role in NF-kappa-B-mediated transcription through regulation of the phosphorylation and the degradation of NFKBIA, the inhibitor of NF-kappa-B. May also play a role in the cellular response to endoplasmic reticulum stress.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Dashurin; DDRGK domain-containing protein 1; UFM1-binding and PCI domain-containing protein 1; UFM1-binding protein 1 containing a PCI domain
Gene Aliases: 1110001I20Rik; 2600009E05Rik; AI326138; C20orf116; DDRGK1; dJ1187M17.3; RGD1309979; SEMDSH; UFBP1
UniProt ID: (Human) Q96HY6, (Mouse) Q80WW9
Entrez Gene ID: (Human) 65992, (Mouse) 77006, (Rat) 296162
blood circulation
positive regulation of cell proliferation
positive regulation of gene expression
negative regulation of gene expression
positive regulation of cell migration
regulation of protein stability
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
ribosome disassembly
regulation of intracellular estrogen receptor signaling pathway
response to endoplasmic reticulum stress
negative regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of transcription from RNA polymerase II promoter
positive regulation of NF-kappaB transcription factor activity
cartilage development
reticulophagy
protein localization to endoplasmic reticulum
protein ufmylation
rescue of stalled ribosome
positive regulation of reticulophagy
positive regulation of plasma cell differentiation
positive regulation of proteasomal protein catabolic process
positive regulation of cell cycle G1/S phase transition
positive regulation of proteolysis involved in cellular protein catabolic process
positive regulation of I-kappaB phosphorylation
negative regulation of IRE1-mediated unfolded protein response
negative regulation of PERK-mediated unfolded protein response
positive regulation of protein localization to endoplasmic reticulum
protein K69-linked ufmylation
protein polyufmylation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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