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DDRGK1 Polyclonal Antibody

View all (5) DDRGK1 antibodies

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DDRGK1 Polyclonal Antibody

Product Details

BS-8252R

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:500
-

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500
-

Immunocytochemistry (ICC/IF)

1:50-1:200
-

ELISA (ELISA)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human DDRGK1, amino acids 81-180.
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Amount

100 µg

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Protein which interacts with the E3 UFM1-protein ligase UFL1 and one of its substrates TRIP4 and is required for TRIP4 ufmylation. Through TRIP4 ufmylation may regulate nuclear receptors-mediated transcription. May play a role in NF-kappa-B-mediated transcription through regulation of the phosphorylation and the degradation of NFKBIA, the inhibitor of NF-kappa-B. May also play a role in the cellular response to endoplasmic reticulum stress.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Dashurin; DDRGK domain-containing protein 1; UFM1-binding and PCI domain-containing protein 1; UFM1-binding protein 1 containing a PCI domain

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Gene Aliases: 1110001I20Rik; 2600009E05Rik; AI326138; C20orf116; DDRGK1; dJ1187M17.3; RGD1309979; SEMDSH; UFBP1

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UniProt ID: (Human) Q96HY6, (Mouse) Q80WW9

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Entrez Gene ID: (Human) 65992, (Mouse) 77006, (Rat) 296162

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Function(s)
protein binding ubiquitin-like protein ligase binding UFM1-modified protein reader activity
Process(es)
blood circulation positive regulation of cell proliferation positive regulation of gene expression negative regulation of gene expression positive regulation of cell migration regulation of protein stability negative regulation of proteasomal ubiquitin-dependent protein catabolic process positive regulation of proteasomal ubiquitin-dependent protein catabolic process ribosome disassembly regulation of intracellular estrogen receptor signaling pathway response to endoplasmic reticulum stress negative regulation of apoptotic process positive regulation of I-kappaB kinase/NF-kappaB signaling positive regulation of transcription from RNA polymerase II promoter positive regulation of NF-kappaB transcription factor activity cartilage development reticulophagy protein localization to endoplasmic reticulum protein ufmylation rescue of stalled ribosome positive regulation of reticulophagy positive regulation of plasma cell differentiation positive regulation of proteasomal protein catabolic process positive regulation of cell cycle G1/S phase transition positive regulation of proteolysis involved in cellular protein catabolic process positive regulation of I-kappaB phosphorylation negative regulation of IRE1-mediated unfolded protein response negative regulation of PERK-mediated unfolded protein response positive regulation of protein localization to endoplasmic reticulum protein K69-linked ufmylation protein polyufmylation
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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