Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
This antibody may cross-react with DDX39B.
Immunogen sequence: MAEQDVEND LLDYDEEEEP QAPQESTPAP PKKDIKGSYV SIHSSGFRDF LLKPELLRAI VDCGFEHPSE VQHECIPQAI LGMDVLCQAK SGMGKTAVFV LATLQQIEPV NGQVTVLVMC HTRELAFQIS KEYERFSKYM PSVKVSVFFG GLSIKKDEEV LKKNCPHVVV GTPGRILALV RNRSFSLKNV KHFVLDECDK MLEQLDMRRD VQEIFRLTPH EKQCMMFSAT LSKDIRPVCR KFMQDPMEVF VDDETKLTLH GLQQYYVKLK DSEKNRKLFD LLDVLEFNQP VTLSAVQGFP AADPGGHQSV WPGDGHRASQ HRL (1-322 aa encoded by BC032128)
This gene encodes a member of the DEAD box protein family. These proteins are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD) and are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene is thought to play a role in the prognosis of patients with gastrointestinal stromal tumors. A pseudogene of this gene is present on chromosome 13. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATP-dependent RNA helicase DDX39; ATP-dependent RNA helicase DDX39A; DEAD (Asp-Glu-Ala-Asp) box polypeptide 39; DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A; DEAD box protein 39; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 39; Nuclear RNA helicase URH49; Nuclear RNA helicase, DECD variant of DEAD box family; UAP56-related helicase, 49 kDa
Gene Aliases: 2610307C23Rik; BAT1; BAT1L; DDX39; DDX39A; DDXL; URH49
UniProt ID: (Human) O00148, (Mouse) Q8VDW0, (Rat) Q5U216
Entrez Gene ID: (Human) 10212, (Mouse) 68278, (Rat) 89827
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