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Product Details
PA5-88219
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:100 | - |
Immunocytochemistry (ICC/IF) |
1:50-1:100 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human DDX3Y |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1.59 mg/mL |
Purification |
Affinity Chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.01% thimerosal |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2804752 |
Product Specific Information
Immunogen sequence: MSHVVVKNDP ELDQQLANLD LNSEKQSGGA STASKGRYIP PHLRNREASK GFHDKDSSGW SCSKDKDAYS SFGSRDSRGK PGYFSERGSG SRGRFDDRGR SDYDGIGNRE RPGFGRFERS GHSRWCDKSV EDDWSKPLPP SERLEQELFS GGNTGINFEK YDDIPVEATG SNCPPHIENF SDIDMGEIIM GNIELTRYTR PTPVQKHAIP; Positive Samples: A-549, B-cell, 293T, A-431, HeLa, Mouse testis, Rat testis; Cellular Location: Cytoplasm, Nucleus
Target Information
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. DDX3Y is one member of DEAD box RNA helicases, encode by the gene locate on the chromosome Y in the azoospermia factor A region.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP-dependent RNA helicase DDX3Y; D1Pas1 related sequence 1; D1Pas1-related sequence 1; DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked; DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked; DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide, Y chromosome; DEAD box protein 3, Y-chromosomal; DEAD-box RNA helicase DEAD2; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide, Y chromosome; mDEAD2; uncharacterized protein LOC364073
Gene Aliases: 8030469F12Rik; D1Pas1-rs1; DBY; DDX3Y; Dead2; RGD1309586
UniProt ID: (Human) O15523, (Mouse) Q62095
Entrez Gene ID: (Human) 8653, (Rat) 364073, (Mouse) 26900
chromosome segregation
metabolic process
extrinsic apoptotic signaling pathway via death domain receptors
response to virus
RNA secondary structure unwinding
positive regulation of gene expression
negative regulation of translation
positive regulation of cell growth
negative regulation of cell growth
negative regulation of protein complex assembly
DNA duplex unwinding
stress granule assembly
intracellular signal transduction
mature ribosome assembly
positive regulation of apoptotic process
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of viral genome replication
innate immune response
positive regulation of translation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of translational initiation
cellular response to arsenic-containing substance
cellular response to osmotic stress
intrinsic apoptotic signaling pathway
positive regulation of G1/S transition of mitotic cell cycle
negative regulation of intrinsic apoptotic signaling pathway
translational initiation
regulation of gene expression
DNA binding
RNA binding
ATP-dependent RNA helicase activity
ATP binding
nucleic acid binding
GTPase activity
ATP-dependent DNA helicase activity
helicase activity
transcription factor binding
poly(A) binding
eukaryotic initiation factor 4E binding
ATPase activity
nucleoside-triphosphatase activity
translation initiation factor binding
RNA stem-loop binding
ribosomal small subunit binding
CTPase activity
poly(A) RNA binding
mRNA 5'-UTR binding
nucleotide binding
hydrolase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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