Invitrogen

DDX3Y Polyclonal Antibody

View all (8) DDX3Y antibodies
Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

PA5-90055

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-
Product Specifications

Species Reactivity

Human, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human DDX3Y (NP_0011161371)
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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.50 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805908

Product Specific Information

Immunogen sequence: MSHVVVKNDP ELDQQLANLD LNSEKQSGGA STASKGRYIP PHLRNREASK GFHDKDSSGW SCSKDKDAYS SFGSRDSRGK PGYFSERGSG SRGRFDDRGR SDYDGIGNRE RPGFGRFERS GHSRWCDKSV EDDWSKPLPP SERLEQELFS GGNTGINFEK YDDIPVEATG SNCPPHIENF SDIDMGEIIM GNIELTRYTR PTPVQKHAIP; Positive Samples: A-549, HeLa, rat testis; Cellular Location: Cytoplasm, Nucleus

Target Information

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. DDX3Y is one member of DEAD box RNA helicases, encode by the gene locate on the chromosome Y in the azoospermia factor A region.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: ATP-dependent RNA helicase DDX3Y; DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked; DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked; DEAD box protein 3, Y-chromosomal; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide, Y chromosome; uncharacterized protein LOC364073

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Gene Aliases: DBY; DDX3Y; RGD1309586

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UniProt ID: (Human) O15523

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Entrez Gene ID: (Human) 8653, (Rat) 364073

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Function(s)
DNA binding RNA binding ATP-dependent RNA helicase activity ATP binding nucleic acid binding GTPase activity ATP-dependent DNA helicase activity helicase activity transcription factor binding poly(A) binding eukaryotic initiation factor 4E binding ATPase activity nucleoside-triphosphatase activity translation initiation factor binding RNA stem-loop binding ribosomal small subunit binding CTPase activity poly(A) RNA binding mRNA 5'-UTR binding
Process(es)
chromosome segregation metabolic process extrinsic apoptotic signaling pathway via death domain receptors response to virus RNA secondary structure unwinding positive regulation of gene expression negative regulation of translation positive regulation of cell growth negative regulation of cell growth negative regulation of protein complex assembly DNA duplex unwinding stress granule assembly intracellular signal transduction mature ribosome assembly positive regulation of apoptotic process negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process positive regulation of cysteine-type endopeptidase activity involved in apoptotic process positive regulation of viral genome replication innate immune response positive regulation of translation positive regulation of transcription from RNA polymerase II promoter positive regulation of translational initiation cellular response to arsenic-containing substance cellular response to osmotic stress intrinsic apoptotic signaling pathway positive regulation of G1/S transition of mitotic cell cycle negative regulation of intrinsic apoptotic signaling pathway translational initiation regulation of gene expression
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