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Invitrogen
DDX4 Polyclonal Antibody
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Product Details
PA5-49689
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide sequence around aa.273~277(T-I-L-V-E)derived from Human DDX4.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody detects endogenous level of total DDX4 protein.
Target Information
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a homolog of VASA proteins in Drosophila and several other species. The gene is specifically expressed in the germ cell lineage in both sexes and functions in germ cell development. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP-dependent RNA helicase DDX4; D-E-A-D (aspartate-glutamate-alanine-aspartate) box polypeptide 4; DEAD (Asp-Glu-Ala-Asp) box polypeptide 4; DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 4; DEAD box polypeptide 4; DEAD box protein 4; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 4; MGC111074; Mvh; mvh / m'vasa; Probable ATP-dependent RNA helicase DDX4; putative ATP-dependent RNA helicase DDX4; rVLG; unnamed protein product; VASA; Vasa homolog; vasa-like gene protein
Gene Aliases: AV206478; DDX4; Mvh; RVLG; VASA
UniProt ID: (Human) Q9NQI0, (Rat) Q64060, (Mouse) Q61496
Entrez Gene ID: (Human) 54514, (Rat) 310090, (Mouse) 13206
male meiosis I
multicellular organism development
spermatogenesis
metabolic process
sperm motility
regulation of protein localization
male meiosis
gamete generation
germ cell development
cell differentiation
gene silencing by RNA
piRNA metabolic process
meiotic cell cycle
transposable element silencing by piRNA-mediated heterochromatin formation
transposable element silencing by piRNA-mediated DNA methylation
RNA secondary structure unwinding
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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