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Invitrogen
DDX41 Polyclonal Antibody
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Product Details
PA5-34550
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 17 amino acid peptide near the amino terminus of human DDX41
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
A suggested positive control is rat brain tissue lysate.
PA5-34550 can be used with blocking peptide PEP-1593.
Target Information
Probable ATP-dependent RNA helicase DDX41 is a DEAD box protein characterized by the conserved motif Asp-Glu-Ala-Asp. It is required during post-transcriptional gene expression and may be involved in pre-mRNA splicing. Mutations affecting the gene can result in myeloproliferative/lymphoproliferative neoplasms, familial (MPLPF).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Abstrakt; DEAD (Asp-Glu-Ala-Asp) box polypeptide 41; DEAD box protein 41; DEAD box protein abstrakt homolog; DEAD-box protein abstrakt; Probable ATP-dependent RNA helicase DDX41; putative RNA helicase; unnamed protein product
Gene Aliases: 2900024F02Rik; AA958953; ABS; AI324246; DDX41; MPLPF
UniProt ID: (Human) Q9UJV9, (Mouse) Q91VN6
Entrez Gene ID: (Human) 51428, (Mouse) 72935, (Rat) 314336
mRNA processing
RNA splicing
RNA secondary structure unwinding
cellular response to interferon-beta
positive regulation of transcription from RNA polymerase II promoter
defense response to virus
metabolic process
mRNA splicing, via spliceosome
apoptotic process
cell proliferation
cell differentiation
positive regulation of type I interferon production
cGAS/STING signaling pathway
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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