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Immunogen sequence: IHRVGRTARA GRSGKAITFV TQYDVELFQR IEHLIGKKLP GFPTQDDEVM MLTERVAEAQ RFARMELREH GEKKKRSRED AGDNDDTEGA IGVRNKVAGG KMKKRKGR
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%.
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene can shuttle between the nucleus and the cytoplasm, and has an RNA-independent ATPase activity. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DEAD (Asp-Glu-Ala-Asp) box polypeptide 47; DEAD box polypeptide 47; DEAD box protein 47; E4-DEAD box protein; Probable ATP-dependent RNA helicase DDX47
Gene Aliases: DDX47; E4-DBP; HQ0256; MSTP162; RRP3
UniProt ID: (Human) Q9H0S4
Entrez Gene ID: (Human) 51202
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