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Bethyl Laboratories
DDX56 Polyclonal Antibody
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FIGURE: 1 / 2
DDX56 Antibody (A302-979A) in IHC (P)
Detection of human DDX56 by immunohistochemistry. Samples: FFPE serial sections of human breast carcinoma. Antibody: Affinity purified rabbit anti-DDX56 (Product # A302-979A) (Lot 1 upper panel) and (Product # A302-978A) (Lot 1 lower panel) used at a dilution of 1:1,000 (1 µg/mL). Detection: DAB.
Product Details
A302-979A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 497 and 547 of human DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 56.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
phosphate/tris citrate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Information
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene shows ATPase activity in the presence of polynucleotides and associates with nucleoplasmic 65S preribosomal particles. This gene may be involved in ribosome synthesis, most likely during assembly of the large 60S ribosomal subunit.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 61-kd nucleolar helicase; ATP-dependent 61 kDa nucleolar RNA helicase; DDX21; DDX56; DEAD (Asp-Glu-Ala-Asp) box helicase 56; DEAD (Asp-Glu-Ala-Asp) box polypeptide 56; DEAD box protein 21; DEAD box protein 56; DEAD-box RNA helicase; nucleolar helicase of 61 kDa; Probable ATP-dependent RNA helicase DDX56; putative nucleolar RNA helicase; unnamed protein product
Gene Aliases: DDX21; DDX26; DDX56; NOH61
UniProt ID: (Human) Q9NY93
Entrez Gene ID: (Human) 54606
cytoplasmic pattern recognition receptor signaling pathway
rRNA processing
protein import into nucleus
positive regulation of neuron projection development
negative regulation of type I interferon production
ribosome biogenesis
modulation by host of viral RNA genome replication
defense response to virus
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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