|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 83 and 175 of Human DERL3|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-31956 targets DERL3 in WB applications and shows reactivity with Human samples.
The PA5-31956 immunogen is synthetic peptide corresponding to a region within amino acids 83 and 175 of Human DERL3.
The protein encoded by this gene belongs to the derlin family, and resides in the endoplasmic reticulum (ER). Proteins that are unfolded or misfolded in the ER must be refolded or degraded to maintain the homeostasis of the ER. This protein appears to be involved in the degradation of misfolded glycoproteins in the ER. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C22orf14; Degradation in endoplasmic reticulum protein 3; Der1-like domain family, member 3; Der1-like protein 3; derlin 3; Derlin-3; DERtrin 3; DERtrin-3; IZP6; LLN2
Gene Aliases: C22orf14; DER3; DERL3; derlin-3; IZP6; LLN2
UniProt ID: (Human) Q96Q80
Entrez Gene ID: (Human) 91319
Molecular Function: receptor
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.