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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 133 and 361 of Human DGCR2|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-30345 targets DGCR2 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-30345 immunogen is recombinant fragment corresponding to a region within amino acids 133 and 361 of Human DGCR2.
Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22. The DGCR2 gene encodes a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
DGS-C; DiGeorge syndrome critical region protein 2; IDD; integral membrane protein deleted in DiGeorge syndrome; integral membrane protein DGCR2/IDD; LAN; SEZ-12
DGCR2; DGS-C; IDD; KIAA0163; LAN; SEZ-12