|Western Blot (WB)||Assay dependent|
|Tested Species reactivity||Human|
|Host / Isotype||Chicken / IgY|
|Immunogen||Amino acids 1-220 of DGCR6.|
|Purification||Antigen affinity chromatography|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
PA1-28256 detects DGCR6 from human samples.
PA1-28256 has been successfully used in Western blot applications.
The PA1-28256 immunogen is: Amino acids 1-220 of DGCR6.
DiGeorge syndrome, and more widely, the CATCH 22 syndrome, are associated with microdeletions in chromosomal region 22q11.2. The product of this gene shares homology with the Drosophila melanogaster gonadal protein, which participates in gonadal and germ cell development, and with the gamma-1 subunit of human laminin. This gene is a candidate for involvement in DiGeorge syndrome pathology and in schizophrenia.
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