Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: METDESPSP LPCGPAGEAV MESRARPFQA LPREQSPPPP LQTSSGAEVM DVGSGGDGQS ELPAEDPFNF YGASLLSKGS FSKGRLLIDP NCSGHSPRTA RHAPAVRKFS PDLKLLKDVK ISVSFTESCR SKDRKVLYTG AERDVRAECG LLLSPVSGDV HACPFGGSVG DGVGIGGESA DKKDEENELD QEKRVEYAVL DELEDFTDNL ELDEEGAGGF TAKAIVQRDR VDEEALNFPY EDDFDNDVDA LLEEGLCAPK KRRTEEKYGG DSDHPSDGET SVQPMMTKIK TVLKSRGRPP TEPL (1-303 aa encoded by BC078147)
This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DiGeorge syndrome critical region 8; DiGeorge syndrome critical region gene 8; Microprocessor complex subunit DGCR8
Gene Aliases: C22orf12; DGCR8; DGCRK6; Gy1; LP4941; pasha
UniProt ID: (Human) Q8WYQ5
Entrez Gene ID: (Human) 54487
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support