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Invitrogen
DGKB Polyclonal Antibody
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FIGURE: 1 / 4
DGKB Antibody (PA5-15416) in IHC (P)
Immunohistochemistry analysis of DGKB in formalin-fixed and paraffin-embedded human cancer tissue. Samples were incubated with DGKB polyclonal antibody (Product # PA5-15416) which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepato... View More
Product Details
PA5-15416
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 773-804 amino acids from the C-terminal region of human DGKB
Conjugate
Form
Liquid
Concentration
2 mg/mL
Purification
Size-exclusion - Dialysis, Ammonium sulfate precipitation
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Diacylglycerol (DAG) is an allosteric activator of protein kinase C. DAG also participates in regulating RAS and RHO family proteins by activating the guanine nucleotide exchange factors VAV and RASGRP1. DAG is also involved in the synthesis of phospholipids and triacylglycerols. Tight regulation of DAG levels is achieved via DAG kinases (DGKs), which remove DAG by phosphorylate it to phosphatidic acid. Several mammalian isozymes of DAGK have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 90 kDa diacylglycerol kinase; DAG kinase beta; DGK-beta; Diacylglycerol kinase beta; diacylglycerol kinase, beta 90kDa; Diglyceride kinase beta
Gene Aliases: 6430574F24; 90kda; C630029D13Rik; DAGK2; DGK; DGK-BETA; DGKB; KIAA0718; mKIAA0718
UniProt ID: (Human) Q9Y6T7, (Mouse) Q6NS52
Entrez Gene ID: (Human) 1607, (Mouse) 217480
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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