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Abnova
DGKG Polyclonal Antibody, MaxPab™
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Product Details
H00001608-D01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DGKG (NP_001074213.1, 1 a.a. approximately 766 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MGEERWVSLT PEEFDQLQKY SEYSSKKIKD ALTEFNEGGS LKQYDPHEPI SYDVFKLFMR AYLEVDLPQP LSTHLFLAFS QKPRHETSDH PTEGASNSEA NSADTNIQNA DNATKADEAC APDTESNMAE KQAPAEDQVA ATPLEPPVPR SSSSESPVVY LKDVVCYLSL LETGRPQDKL EFMFRLYDSD ENGLLDQAEM DCIVNQMLHI AQYLEWDPTE LRPILKEMLQ GMDYDRDGFV SLQEWVHGGM TTIPLLVLLG MDDSGSKGDG RHAWTMKHFK KPTYCNFCHI MLMGVRKQGL CCTYCKYTVH ERCVSRNIPG CVKTYSKAKR SGEVMQHAWV EGNSSVKCDR CHKSIKCYQS VTARHCVWCR MTFHRKCELS TLCDGGELRD HILLPTSICP ITRDRPGEKS DGCVSAKGEL VMQYKIIPTP GTHPLLVLVN PKSGGRQGER LNFFRDTPDF RVLACGGDGT VGWILDCIDK ANFAKHPPVA VLPLGTGNDL ARCLRWGGGY EGGSLTKILK DIEQSPLVML DRWHLEVIPR EEVENGDQVP YSIMNNYFSI GVDASIAHRF HVMREKHPEK FNSRMKNKLW YFEFGTSETF AATCKKLHDH IELECDGVGV DLSNIFLEGI AILNIPSMYG GTNLWGENKK NRAVIRESRK GVTDPKELKF CVQDLSDQLL EVVGLEGAME MGQIYTGLKS AGRRLAQCAS VTIRTNKLLP MQVDGEPWMQ PCCTIKITHK NQAPMMMGPP QKSSFFSLRR KSRSKD
Target Information
This gene encodes an enzyme that is a member of the type I subfamily of diacylglycerol kinases, which are involved in lipid metabolism. These enzymes generate phosphatidic acid by catalyzing the phosphorylation of diacylglycerol, a fundamental lipid second messenger that activates numerous proteins, including protein kinase C isoforms, Ras guanyl nucleotide-releasing proteins and some transient receptor potential channels. Diacylglycerol kinase gamma has been implicated in cell cycle regulation and in the negative regulation of macrophage differentiation in leukemia cells. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DAG kinase gamma; DGK-gamma; Diacylglycerol kinase gamma; diacylglycerol kinase, gamma 90kDa; diacylglyerol kinase gamma; Diglyceride kinase gamma; unnamed protein product
Gene Aliases: DAGK3; DGK-GAMMA; DGKG
UniProt ID: (Human) P49619
Entrez Gene ID: (Human) 1608
lipid metabolic process
phosphatidic acid biosynthetic process
signal transduction
phospholipase C-activating G-protein coupled receptor signaling pathway
platelet activation
intracellular signal transduction
diacylglycerol metabolic process
glycerolipid metabolic process
lipid phosphorylation
regulation of dendrite development
negative regulation of phospholipase C/protein kinase C signal transduction
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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