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Proteintech
DGKZ Polyclonal Antibody
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Product Details
32124-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DGKZ fusion protein Ag37336
Conjugate
Form
Liquid
Concentration
450 µg/mL
Amount
67.5 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Sequence of this protein is as follows: LDPELLGASA RPDLPTPTSP LPTSPCSPTP RSLQGDAAPP QGEELIEAAK RNDFCKLQEL HRAGGDLMHR DEQSRTLLHH AVSTGSKDVV RYLLDHAPPE ILDAVEENGE TCLHQAAALG QRTICHYIVE AGASLMKTDQ QGDTPRQRAE KAQDTELAAY LENRQHYQMI QREDQETAV
Target Information
The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 104 kDa diacylglycerol kinase; DAG kinase DAGK6; DAG kinase zeta; DGK-IV; DGK-zeta; Diacylglycerol kinase zeta; diacylglycerol kinase, zeta 104kDa; Diglyceride kinase; Diglyceride kinase zeta; protein kinase; unnamed protein product
Gene Aliases: DAGK5; DAGK6; DGK-ZETA; DGKZ; E130307B02Rik; ENSMUSG00000075035; F730209L11Rik; hDGKzeta; mDGK[z]
UniProt ID: (Human) Q13574, (Mouse) Q80UP3, (Rat) O08560
Entrez Gene ID: (Human) 8525, (Mouse) 104418, (Rat) 81821
lipid metabolic process
phosphatidic acid biosynthetic process
signal transduction
phospholipase C-activating G-protein coupled receptor signaling pathway
cell migration
platelet activation
mitotic G1 DNA damage checkpoint
intracellular signal transduction
diacylglycerol metabolic process
glycerolipid metabolic process
lipid phosphorylation
negative regulation of T cell receptor signaling pathway
protein kinase C-activating G-protein coupled receptor signaling pathway
phosphorylation
negative regulation of catalytic activity
negative regulation of mitotic cell cycle
negative regulation of Ras protein signal transduction
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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