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Product Details
PA5-77942
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human DHCR7. The exact sequence is proprietary.
Conjugate
Unconjugated
Form
Liquid
Concentration
0.98 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
AB_2735718
Product Specific Information
Positive Control: HepG2 (boiled), HepG2 MF (boiled), HepG2 (unboiled), HepG2 MF (unboiled)
Predicted Reactivity: Bovine (96%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Production of cholesterol by reduction of C7-C8 double bond of 7-dehydrocholesterol (7-DHC).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 7-dehydrocholesterol reductase; 7-DHC reductase; delta-7-dehydrocholesterol reductase; Delta7-sterol reductase; putative sterol reductase SR-2; Sterol Delta(7)-reductase; sterol delta-7-reductase; Sterol reductase SR-2
Gene Aliases: AA409147; D7SR; DHCR7; SLOS
UniProt ID: (Human) Q9UBM7, (Mouse) O88455, (Rat) Q9Z2Z8
Entrez Gene ID: (Human) 1717, (Mouse) 13360, (Rat) 64191
Molecular Function:
reductase
blood vessel development
cholesterol biosynthetic process
post-embryonic development
cell differentiation
lung development
cholesterol biosynthetic process via desmosterol
cholesterol biosynthetic process via lathosterol
multicellular organism growth
regulation of cell proliferation
regulation of cholesterol biosynthetic process
oxidation-reduction process
lipid metabolic process
steroid biosynthetic process
steroid metabolic process
cholesterol metabolic process
sterol biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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