The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane. [provided by RefSeq, Jul 2008].
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Protein Aliases: DHOdehase; Dihydroorotate dehydrogenase (quinone), mitochondrial; dihydroorotate dehydrogenase, mitochondrial; Dihydroorotate oxidase; human complement of yeast URA1
Gene Aliases: 2810417D19Rik; AI834883; DHOdehase; DHODH; POADS; URA1
Molecular Function: dehydrogenase