Immunogen sequence: TEKCLKETTE EIRQMGTECH YFICDVGNRE EVYQTAKAVR EKVGDITILV NNAAVVHGKS LMDSDDDALL KSQHINTLGQ FWTTKAFLPR MLELQNGHIV CLNSVLALSA IPG
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA).
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Protein Aliases: DD83.1; dehydrogenase/reductase (SDR family) member 3; dehydrogenase/reductase member 3; member 1; RDH17; retinal dehydrogenase/reductase family member 3; Retinal short-chain dehydrogenase/reductase 1; Retinol dehydrogenase 17; retSDR1; Rsdr1; SDR1; SDR16C1; short chain dehydrogenase/reductase family 16C; Short chain dehydrogenase/reductase family 16C member 1; short chain dehydrogenase/reductase family 16C, member 1; short-chain dehydrogenase/reductase 1; Short-chain dehydrogenase/reductase 3
Gene Aliases: DD83.1; DHRS3; RDH17; retSDR1; Rsdr1; SDR1; SDR16C1; UNQ2424/PRO4983