|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthesized peptide derived from internal of human DHRS4.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4, with 50% glycerol|
|Contains||0.02% sodium azide|
The antibody detects endogenous levels of total DHRS4 protein.
Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co-factor, but with much lower efficiency. Reduces alkyl phenyl ketones and alpha-dicarbonyl compounds with aromatic rings, such as pyrimidine-4-aldehyde, 3-benzoylpyridine, 4-benzoylpyridine, menadione and 4-hexanoylpyridine. Has no activity towards aliphatic aldehydes and ketones By similarity. Fransen M., Biochem. J. 340:561-568(1999). Furukawa A., Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases. Du J., Yi Chuan Xue Bao 31:661-667(2004).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CR; dehydrogenase/reductase (SDR family) member 4 like 2A; Dehydrogenase/reductase SDR family member 4; NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase; NADPH-dependent retinol dehydrogenase/reductase; NRDR; Peroxisomal short-chain alcohol dehydrogenase; PSCD; SCAD-SRL; SDR25C2; Short chain dehydrogenase/reductase family 25C member 2; short chain dehydrogenase/reductase family 25C, member 1; short chain dehydrogenase/reductase family 25C, member 2; Short-chain dehydrogenase/reductase family member 4
Gene Aliases: CR; DHRS4; NRDR; PHCR; PSCD; SCAD-SRL; SDR-SRL; SDR25C1; SDR25C2; UNQ851/PRO1800
UniProt ID: (Human) Q20CR0
Entrez Gene ID: (Human) 10901
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