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Proteintech
DHX29 Polyclonal Antibody
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Product Details
13923-1-AP
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DHX29 Fusion Protein Ag4938 (1025-1369 aa encoded by BC056219)
Conjugate
Form
Liquid
Concentration
0.22 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: CNLGSPEDF LSKALDPPQL QVISNAMNLL RKIGACELNE PKLTPLGQHL AALPVNVKIG KMLIFGAIFG CLDPVATLAA VMTEKSPFTT PIGRKDEADL AKSALAMADS DHLTIYNAYL GWKKARQEGG YRSEITYCRR NFLNRTSLLT LEDVKQELIK LVKAAGFSSS TTSTSWEGNR ASQTLSFQEI ALLKAVLVAG LYDNVGKIIY TKSVDVTEKL ACIVETAQGK AQVHPSSVNR DLQTHGWLLY QEKIRYARVY LRETTLITPF PVLLFGGDIE VQHRERLLSI DGWIYFQAPV KIAVIFKQLR VLIDSVLRKK LENPKMSLEN DKILQIITEL IKTENN (1025-1369 aa encoded by BC056219)
Target Information
DNA helicase and probable main scaffold component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair; according to PubMed:20687897 the contribution to DNA double-strand break repair appears to be largely indirect through transcriptional regulation. Recruited by YY1 to YY1-activated genes, where it acts as an essential coactivator. Binds DNA. In vitro, has double-stranded DNA-dependent ATPase activity. Involved in UV-damage excision repair, DNA replication and chromosome segregation during normal cell division cycle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP-dependent RNA helicase DHX29; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 29; DEAH (Asp-Glu-Ala-His) box polypeptide 29; DEAH box protein 29; Nucleic acid helicase DDXx
Gene Aliases: 3732415M03; AU043276; DDX29; Ddxx; DHX29; E130202M19Rik
UniProt ID: (Human) Q7Z478, (Mouse) Q6PGC1
Entrez Gene ID: (Human) 54505, (Mouse) 218629, (Rat) 100362324
translation initiation factor activity
ATP-dependent RNA helicase activity
ATP binding
ribosomal small subunit binding
poly(A) RNA binding
cadherin binding involved in cell-cell adhesion
nucleotide binding
nucleic acid binding
helicase activity
ATP-dependent helicase activity
hydrolase activity
RNA helicase
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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