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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||C-terminus of the human DIABLO protein.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-4267 detects DIABLO protein from human samples.
PA1-4267 has been successfully used in Western blot procedures.
PA1-4267 immunizing peptide corresponds to the C-terminus of the human DIABLO protein.
DIABLO (direct IAP binding protein with low pI, smac) is a novel protein that can bind mammalian IAP homolog A (MIHA, also known as XIAP), and can also interact with MIHB and MIHC and the baculoviral IAP, OpIAP. DIABLO may promote apoptosis by binding to IAPs and preventing them from inhibiting caspases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
diablo, IAP-binding mitochondrial protein; diablo-like protein; direct IAP-binding protein with low pI; second mitochondria-derived activator of caspase; Smac; Smac protein
DFNA64; DIABLO; SMAC