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Invitrogen
DIAPH1 Polyclonal Antibody
Product Details
PA5-21409
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 1 and 237 of DIAPH1 (Uniprot ID#O60610)
Conjugate
Form
Liquid
Concentration
0.69 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11153295
Product Specific Information
Recommended positive controls: A431, H1299, HeLa, HepG2, Molt-4, Raji.
Predicted reactivity: Mouse (95%), Rat (94%), Pig (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: diaphanous 1; diaphanous-1; diaphanous-related formin 1; Diaphanous-related formin-1; DRF1; FLJ25265; p140DIA; Protein diaphanous homolog 1
Gene Aliases: DFNA1; DIA1; DIAP1; DIAPH1; DRF1; hDIA1; LFHL1; SCBMS
UniProt ID: (Human) O60610
Entrez Gene ID: (Human) 1729
cytoskeleton organization
sensory perception of sound
regulation of cell shape
actin filament polymerization
positive regulation of cell migration
regulation of microtubule-based process
protein localization to microtubule
regulation of release of sequestered calcium ion into cytosol
cellular response to histamine
regulation of cell motility
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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