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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 981 and 1272 of Human DIAPH1|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 40% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-27607 targets DIAPH1 in IF, IHC-P, and WB applications and shows reactivity with Human samples.
The PA5-27607 immunogen is recombinant fragment corresponding to a region within amino acids 981 and 1272 of Human DIAPH1.
This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
DFNA1; DIA1; diaphanous-related formin 1; diaphanous-related formin-1; DRF1; hDIA1; LFHL1; protein diaphanous homolog 1
D18Wsu154e; DFNA1; DIA1; DIAP1; DIAPH1; DRF1; hDIA1; LFHL1; p140mDia; SCBMS