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DIO2 Polyclonal Antibody
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FIGURE: 1 / 2
DIO2 Antibody (BS-3673R) in IHC (P)
Paraformaldehyde-fixed, paraffin embedded Mouse stomach; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with DIO2 Polyclonal Antibody, Unconjugated (bs-3673R) at 1:400 overnight at 4°C, followed by a conjugated secondary antibody for 20 minu... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
BS-3673R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human DIO2, amino acids 101-200.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine by outer ring deiodination to bioactive 3,3',5-triiodothyronine residues encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: deiodinase, iodothyronine type II; deiodinase, iodothyronine, type 2; deiodinase, iodothyronine, type II; deiodinase-2; deiodonase-2; iodothyronine type II deiodinase; selenoprotein; selenoprotein Y; thyroxine deiodinase; thyroxine deiodinase, type II; thyroxine type II; type 2 DI; type 2 iodothyronine deiodinase; type-II 5' deiodinase; type-II 5'-deiodinase; type-II 5'deiodinase; unnamed protein product
Gene Aliases: 5DII; D2; DIOII; SELENOY; SelY; TXDI2
UniProt ID: (Human) Q92813, (Mouse) Q9Z1Y9, (Rat) P70551
Entrez Gene ID: (Human) 1734, (Mouse) 13371, (Rat) 65162
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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