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|Tested species reactivity||Mouse|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (EVKKHQNQEDRC) corresponding to the internal amino acids of DIO2|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody is predicted to react with human, porcine and rat based on sequence homology.
The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine by outer ring deiodination to bioactive 3,3',5-triiodothyronine residues encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence , which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
deiodinase, iodothyronine, type II; DIO2; iodothyronine type II deiodinase; SelY; thyroxine deiodinase, type II; TXDI2; type 2 DI; type 2 iodothyronine deiodinase; type II iodothyronine deiodinase; type II iodothyronine deiodinaseN: type-II 5'deiodinase; type-II 5' deiodinase; type-II 5'-deiodinase
5DII; AI324267; Dio2; DIOII