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Product Details
A305-859A
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A region between residue 475 and 525 of human DIS3-like exonuclease 2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
phosphate/tris citrate, pH 7.0 to 8.0
Contains
0.09% sodium azide
Storage conditions
4° C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
DIS3L2 encodes a protein that is similar in sequence to 3'/5' exonucleolytic subunits of the RNA exosome. The exosome is a large multimeric ribonucleotide complex responsible for degrading various RNA substrates. Several transcript variants, some protein-coding and some not, have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DIS3 mitotic control homolog-like 2; DIS3-like exonuclease 2; DIS3L2; family with sequence similarity 6, member A; hDIS3L2
Gene Aliases: DIS3L2; FAM6A; hDIS3L2; PRLMNS
UniProt ID: (Human) Q8IYB7
Entrez Gene ID: (Human) 129563
nuclear-transcribed mRNA catabolic process, exonucleolytic
rRNA processing
mitotic nuclear division
negative regulation of cell proliferation
miRNA catabolic process
rRNA catabolic process
stem cell population maintenance
nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
cell division
mitotic sister chromatid separation
RNA phosphodiester bond hydrolysis, exonucleolytic
polyuridylation-dependent mRNA catabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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