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DIS3L2 Antibody (H00129563-B01P) in WB
Western Blot analysis of DIS3L2 expression in transfected 293T cell line (H00129563-T01) by DIS3L2 MaxPab polyclonal antibody.
Lane 1: MGC42174 transfected lysate(68.09 KDa).
Lane 2: Non-transfected lysate.
Lane 1: MGC42174 transfected lysate(68.09 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00129563-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DIS3L2 (AAH36113.2, 1 a.a. approximately 619 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MSHPDYRMNL RSLGTHRGVS AVAGPHDIGA SPGDKKSKNR STRGKKKSIF ETYMSKEDVS EGLKRGTLIQ GVLRINPKKF HEAFIPSPDG DRDIFIDGVV ARNRALNGDL VVVKLLPEEH WKVVKPESND KETEAAYESD IPEELCGHHL PQQSLKSYND SPDVIVEAQF DGSDSEDGHG ITQNVLVDGV KKLSVCVSEK GREDGDAPVT KDETTCISQD TRALSEKSLQ RSAKVVYILE KKHSRAATGF LKLLADKNSE LFRKYALFSP SDHRVPRIYV PLKDCPQDFV ARPKDYANTL FICRIVDWKE DCNFALGQLA KSLGQAGEIE PETEGILTEY GVDFSDFSSE VLECLPQGLP WTIPPEEFSK RRDLRKDCIF TIDPSTARDL DDALSCKPLA DGNFKVGVHI ADVSYFVPEG SDLDKVAAER ATSVYLVQKV VPMLPRLLCE ELCSLNPMSD KLTFSVIWTL TPEGKILDEW FGRTIIRSCT KLSYEHAQSM IESPTEKIPA KELPPISPEH SSEEVHQAVL NLHGIAKQLR QQRFVDGALR LDQLKLAFTL DHETGLPQGC HIYEYRESNK PCCAGTPRPK QGCSVTWWNS ATRWGCPWTS APQEPSIKA
Target Information
DIS3L2 encodes a protein that is similar in sequence to 3'/5' exonucleolytic subunits of the RNA exosome. The exosome is a large multimeric ribonucleotide complex responsible for degrading various RNA substrates. Several transcript variants, some protein-coding and some not, have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DIS3 mitotic control homolog-like 2; DIS3-like exonuclease 2; DIS3L2; family with sequence similarity 6, member A; hDIS3L2
Gene Aliases: DIS3L2; FAM6A; hDIS3L2; PRLMNS
UniProt ID: (Human) Q8IYB7
Entrez Gene ID: (Human) 129563
nuclear-transcribed mRNA catabolic process, exonucleolytic
rRNA processing
mitotic nuclear division
negative regulation of cell proliferation
miRNA catabolic process
rRNA catabolic process
stem cell population maintenance
nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
cell division
mitotic sister chromatid separation
RNA phosphodiester bond hydrolysis, exonucleolytic
polyuridylation-dependent mRNA catabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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