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Invitrogen
DISP2 Polyclonal Antibody
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FIGURE: 1 / 2
DISP2 Antibody (PA5-20631) in WB
Western blot was performed using Anti-DISP2 Polyclonal Antibody (Product # PA5-20631) and a 150 kDa band corresponding to DISP2 was observed across cell lines and tissues tested. Membrane enriched cell extracts (30 µg lysate) of Neuro-2a (Lane 1), RAW 264.7 (Lane 2), Mouse Brain (Lane 3), Rat Brain (Lane 4) and Mouse Uterus (Lane 5) were electrophoresed using Novex® NuPAGE® 4-12 % Bis-Tris gel (Product # NP0322BOX). Resolved proteins were then transferred onto a nitrocellulose membrane (Product # IB23001) by iBlot® 2 Dry Blotting System (P... View More
Product Details
PA5-20631
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 19 amino acid peptide from near the carboxy terminus of human Disp2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
A suggested positive control is rat brain tissue lysate.
PA5-20631 can be used with blocking peptide PEP-0751.
Target Information
DISP2, also known as dispatched homolog 2, is a protein that plays a critical role in the regulation of the hedgehog signaling pathway. It is involved in the transport and release of hedgehog ligands, which are important for cellular differentiation and tissue development. Mutations in the DISP2 gene have been associated with various developmental disorders, including holoprosencephaly and cleft lip and palate. DISP2 is also being studied as a potential therapeutic target in cancer, as the hedgehog pathway is frequently dysregulated in various types of tumors
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: dispatched B; dispatched homolog 2; Protein dispatched homolog 2
Gene Aliases: AI840597; B230210L08Rik; C15orf36; DISP2; DISPB; HsT16908; KIAA1742; LINC00594; mKIAA1742
UniProt ID: (Human) A7MBM2, (Mouse) Q8CIP5
Entrez Gene ID: (Human) 85455, (Mouse) 214240, (Rat) 311324
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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