This antibody is predicted to react with bovine, canine, porcine and rat based on sequence homology.
This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.
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Protein Aliases: dickkopf (Xenopus laevis) homolog 1; dickkopf 1 homolog; dickkopf homolog 1 (Xenopus laevis); dickkopf related protein-1; Dickkopf-1; dickkopf-1 like; dickkopf-like protein 1; Dickkopf-related protein 1; DKK-1; DKK1; hDkk-1; SK
Gene Aliases: DKK-1; DKK1; SK; UNQ492/PRO1008
UniProt ID: (Human) O94907
Entrez Gene ID: (Human) 22943