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DLC1 Polyclonal Antibody
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Product Details
BS-5801R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human DLC1, amino acids 1-80.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes a GTPase-activating protein that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ARHGAP 7; Deleted in liver cancer 1 protein; Deleted in liver cancer 1 protein homolog; DLC 1; DLC-1; epididymis secretory sperm binding protein; FLJ21120; HP protein; p122 RhoGAP; p122-RhoGAP; p122RhoGAP ortholog; rho GTPase activating protein 7; Rho GTPase-activating protein 7; Rho-GTPase-activating protein 7; Rho-type GTPase-activating protein 7; StAR-related lipid; StAR-related lipid transfer (START) domain containing 12; StAR-related lipid transfer protein 12; STARD 12; StARD12; START domain-containing protein 12; transfer protein 12; unnamed protein product
Gene Aliases: A730069N07Rik; ARHGAP7; dlc-1; DLC1; HP; KIAA1723; p122-RhoGAP; RhoGAP; STARD12
UniProt ID: (Human) Q96QB1, (Mouse) Q9R0Z9
Entrez Gene ID: (Human) 10395, (Mouse) 50768, (Rat) 58834
neural tube closure
heart morphogenesis
signal transduction
negative regulation of cell proliferation
hindbrain morphogenesis
actin cytoskeleton organization
negative regulation of cell migration
forebrain development
regulation of Rho protein signal transduction
negative regulation of Rho protein signal transduction
intracellular signal transduction
focal adhesion assembly
regulation of small GTPase mediated signal transduction
negative regulation of stress fiber assembly
negative regulation of focal adhesion assembly
positive regulation of execution phase of apoptosis
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
cytoskeleton organization
activation of phospholipase C activity
regulation of cell shape
regulation of actin cytoskeleton organization
positive regulation of protein dephosphorylation
positive regulation of GTPase activity
Rho protein signal transduction
cellular response to insulin stimulus
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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