FIGURE: 1 / 1
Positive test controls include: Mouse lung. The target is usually found in the following locations: Cell junction, Cytoplasm, Membrane, Peripheral membrane protein, focal adhesion.
This gene encodes a GTPase-activating protein that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.
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Protein Aliases: ARHGAP 7; Deleted in liver cancer 1 protein homolog; DLC 1; DLC-1; FLJ21120; p122 RhoGAP; p122-RhoGAP; rho GTPase activating protein 7; Rho GTPase-activating protein 7; Rho-type GTPase-activating protein 7; StAR-related lipid; StAR-related lipid transfer protein 12; STARD 12; StARD12; START domain-containing protein 12; transfer protein 12
Gene Aliases: A730069N07Rik; Arhgap7; dlc-1; Dlc1; HP; RhoGAP; STARD12
UniProt ID: (Mouse) Q9R0Z9