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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:1,000 | View 2 publications 2 publications |
Immunohistochemistry (IHC) |
- | View 6 publications 6 publications |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:200 | - |
Flow Cytometry (Flow) |
Assay-dependent | View 1 publication 1 publication |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Human, Mouse, Pig, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
DLK1 Fusion Protein Ag0991 (83-383 aa encoded by BC007741) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.34 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.1% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: ELCDRDVRA CSSAPCANNG TCVSLDDGLY ECSCAPGYSG KDCQKKDGPC VINGSPCQHG GTCVDDEGRA SHASCLCPPG FSGNFCEIVA NSCTPNPCEN DGVCTDIGGD FRCRCPAGFI DKTCSRPVTN CASSPCQNGG TCLQHTQVSY ECLCKPEFTG LTCVKKRALS PQQVTRLPNG YGLAYRLTPG VHELPVQQPE HRILKVSMKE LNKKTPLLTE GQAICFTILG VLTSLVVLGT VGIVFLNKCE TWVSNLRYNH MLRKKKNLLL QYNSGEDLAV NIIFPEKIDM TTFSKEAGDE EI (83-383 aa encoded by BC007741)
The Delta-like 1 homolog (DLK1) is a transmembrane protein containing six epidermal growth factor repeats. It is involved in the differentiation of several cell types, including adipocytes and is also thought to be a tumor suppressor. The DLK1 gene is one of several imprinted genes located in a region on chromosome 14q32; certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). DLK1 is expressed from the paternal allele; a polymorphism within this gene has been associated with child and adolescent obesity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Adipocyte differentiation inhibitor protein; delta-like 1 homolog; DLK-1; FA1; Fetal antigen 1; pG2; Preadipocyte factor 1; preadipocyte factor-1; PREF; Pref-1; Protein delta homolog 1; secredeltin; stromal cell derived protein 1
Gene Aliases: AW742678; Delta1; DLK; DLK-1; DLK1; DlkI; FA1; Ly107; Peg9; pG2; Pref-1; PREF1; Scp-1; SCP1; ZOG
UniProt ID: (Human) P80370, (Mouse) Q09163, (Rat) O70534
Entrez Gene ID: (Human) 8788, (Mouse) 13386, (Rat) 114587
Molecular Function:
membrane-bound signaling molecule
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