Proteintech

DLL1 Polyclonal Antibody

View all (22) DLL1 antibodies

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Questions & Answers

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DLL1 Antibody in Western Blot (WB) — Human placenta tissue were subjected to SDS PAGE followed by western blot with 20230-1-AP (DLL1-Specific antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

DLL1 Antibody in Western Blot (WB) — Mouse lung tissue were subjected to SDS PAGE followed by western blot with 20230-1-AP (DLL1-Specific antibody) at dilution of 1:100 incubated at room temperature for 1.5 hours.

Product Details

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1000

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide

Conjugate

Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Product Specific Information

The antibody is specific to the protein DLL1.

Target Information

Delta-like protein 1 (Dlk1, DLL1) is a transmembrane protein characterized by epidermal growth factor (EGF)-like repeats. DLL1, which is also known as preadipocyte factor 1 (pref-1) because of its ability to inhibit preadipocyte differentiation, regulates the differentiation of several other cell types. It is a ligand for Notch receptor. It blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: delta like-1; Delta-like protein 1; Delta1; Dll1-derived cell-associated form; Dll1-EC; Dll1-IC; Dll1-intracellular form; Dll1-soluble form; Dll1-TMIC; Drosophila Delta homolog 1; H-Delta-1; OTTHUMP00000017690

Gene Aliases: Delta; DELTA1; DL1; DLL1; UNQ146/PRO172

UniProt ID: (Human) O00548, (Mouse) Q61483

Entrez Gene ID: (Human) 28514, (Mouse) 13388

in utero embryonic development somitogenesis somite specification heart looping cell communication Notch signaling pathway cell-cell signaling multicellular organism development determination of left/right symmetry compartment pattern specification nervous system development organ morphogenesis auditory receptor cell fate commitment cell differentiation negative regulation of interleukin-10 production inner ear morphogenesis odontogenesis of dentin-containing tooth auditory receptor cell differentiation negative regulation of cell differentiation negative regulation of auditory receptor cell differentiation negative regulation of myeloid cell differentiation negative regulation of neuron differentiation positive regulation of Notch signaling pathway positive regulation of transcription from RNA polymerase II promoter inner ear development regulation of neurogenesis Notch signaling involved in heart development left/right axis specification cell fate determination marginal zone B cell differentiation type B pancreatic cell development Notch receptor processing regulation of blood pressure positive regulation of cell proliferation negative regulation of cell proliferation proximal/distal pattern formation astrocyte development regulation of somitogenesis spinal cord development cerebellar molecular layer formation cerebellar Purkinje cell layer structural organization hemopoiesis regulation of cell adhesion negative regulation of epithelial cell differentiation negative regulation of glial cell apoptotic process organ growth regulation of growth negative regulation of epidermal cell differentiation negative regulation of myoblast differentiation positive regulation of endocytosis lateral inhibition skeletal muscle tissue growth regulation of skeletal muscle tissue growth positive regulation of skeletal muscle tissue growth neuron fate specification regulation of cell division retina development in camera-type eye retina morphogenesis in camera-type eye Notch signaling pathway involved in arterial endothelial cell fate commitment nephron development proximal tubule development loop of Henle development clathrin-mediated endocytosis endothelial tip cell fate specification neuronal stem cell population maintenance skin epidermis development regulation of vascular endothelial growth factor signaling pathway positive regulation of sprouting angiogenesis regulation of energy homeostasis

Process(es)

Notch binding calcium ion binding protein binding Tat protein binding scaffold protein binding