Proteintech

DLL1 Polyclonal Antibody

View all (22) DLL1 antibodies

Questions & Answers

Questions & Answers

Product Image Gallery

DLL1 Antibody in Western Blot (WB) — Human placenta tissue were subjected to SDS PAGE followed by western blot with 20230-1-AP (DLL1-Specific antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

DLL1 Antibody in Western Blot (WB) — Mouse lung tissue were subjected to SDS PAGE followed by western blot with 20230-1-AP (DLL1-Specific antibody) at dilution of 1:100 incubated at room temperature for 1.5 hours.

Product Details

20230-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:1,000	View 2 publications 2 publications

Product Specifications
Species Reactivity	Human, Mouse
Published species	Human, Mouse
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	Peptide
Conjugate	Unconjugated
Form	Liquid
Concentration	0.13 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20°C

Product Specific Information

The antibody is specific to the protein DLL1.

Target Information

Delta-like protein 1 (Dlk1, DLL1) is a transmembrane protein characterized by epidermal growth factor (EGF)-like repeats. DLL1, which is also known as preadipocyte factor 1 (pref-1) because of its ability to inhibit preadipocyte differentiation, regulates the differentiation of several other cell types. It is a ligand for Notch receptor. It blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Modification of α2,6-sialylation mediates the invasiveness and tumorigenicity of non-small cell lung cancer cells in vitro and in vivo via Notch1/Hes1/MMPs pathway.

International journal of cancer

Yuan Q,Chen X,Han Y,Lei T,Wu Q,Yu X,Wang L,Fan Z,Wang S

Thu Nov 01 00:00:00 EDT 2018

MiR-34a-5p promotes multi-chemoresistance of osteosarcoma through down-regulation of the DLL1 gene.

Scientific reports

Pu Y,Zhao F,Wang H,Cai S

Fri Mar 10 00:00:00 EST 2017

Bioinformatics

Protein Aliases: delta like-1; Delta-like protein 1; Delta1; Dll1-derived cell-associated form; Dll1-EC; Dll1-IC; Dll1-intracellular form; Dll1-soluble form; Dll1-TMIC; Drosophila Delta homolog 1; H-Delta-1; OTTHUMP00000017690

Gene Aliases: Delta; DELTA1; DL1; DLL1; UNQ146/PRO172

UniProt ID: (Human) O00548, (Mouse) Q61483

Entrez Gene ID: (Human) 28514, (Mouse) 13388

in utero embryonic development somitogenesis somite specification heart looping cell communication Notch signaling pathway cell-cell signaling multicellular organism development determination of left/right symmetry compartment pattern specification nervous system development organ morphogenesis auditory receptor cell fate commitment cell differentiation negative regulation of interleukin-10 production inner ear morphogenesis odontogenesis of dentin-containing tooth auditory receptor cell differentiation negative regulation of cell differentiation negative regulation of auditory receptor cell differentiation negative regulation of myeloid cell differentiation negative regulation of neuron differentiation positive regulation of Notch signaling pathway positive regulation of transcription from RNA polymerase II promoter inner ear development regulation of neurogenesis Notch signaling involved in heart development left/right axis specification cell fate determination marginal zone B cell differentiation type B pancreatic cell development Notch receptor processing regulation of blood pressure positive regulation of cell proliferation negative regulation of cell proliferation proximal/distal pattern formation astrocyte development regulation of somitogenesis spinal cord development cerebellar molecular layer formation cerebellar Purkinje cell layer structural organization hemopoiesis regulation of cell adhesion negative regulation of epithelial cell differentiation negative regulation of glial cell apoptotic process organ growth regulation of growth negative regulation of epidermal cell differentiation negative regulation of myoblast differentiation positive regulation of endocytosis lateral inhibition skeletal muscle tissue growth regulation of skeletal muscle tissue growth positive regulation of skeletal muscle tissue growth neuron fate specification regulation of cell division retina development in camera-type eye retina morphogenesis in camera-type eye Notch signaling pathway involved in arterial endothelial cell fate commitment nephron development proximal tubule development loop of Henle development clathrin-mediated endocytosis endothelial tip cell fate specification neuronal stem cell population maintenance skin epidermis development regulation of vascular endothelial growth factor signaling pathway positive regulation of sprouting angiogenesis regulation of energy homeostasis

Process(es)

Notch binding calcium ion binding protein binding Tat protein binding scaffold protein binding