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Proteintech

DLL1 Polyclonal Antibody

View all (22) DLL1 antibodies

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DLL1 Polyclonal Antibody

Product Details

28544-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:5,000
-

ELISA (ELISA)

Assay-dependent
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Antigen affinity chromatography

Storage buffer

PBS with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

Product Specific Information

Immunogen sequence: CVRLRLQKHR PPADPCRGET ETMNNLANCQ REKDISVSII GATQIKNTNK KADFHGDHSA DKNGFKARYP AVDYNLVQDL KGDDTAVRDA HSKRDTKCQP QGSSGEEKGT PTTLRGGEAS ERKRPDSGCS TSKDTKYQSV YVISEEKD

Target Information

Delta-like protein 1 (DLL1) is a transmembrane protein characterized by epidermal growth factor (EGF)-like repeats. It is a ligand for Notch receptor. It blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: delta like-1; delta-like 1; delta-like ligand 1; delta1; drosophila Delta homolog 1; DSL ligand; epididymis secretory sperm binding protein; H-Delta-1; Notch ligand; OTTHUMP00000017690; unnamed protein product

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Gene Aliases: Delta; DELTA1; DL1; NEDBAS

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UniProt ID: (Human) O00548, (Rat) P97677, (Mouse) Q61483

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Entrez Gene ID: (Human) 28514, (Rat) 84010, (Mouse) 13388

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Function(s)
Notch binding calcium ion binding protein binding Tat protein binding receptor agonist activity scaffold protein binding
Process(es)
cell fate determination somitogenesis somite specification heart looping marginal zone B cell differentiation type B pancreatic cell development cell communication Notch signaling pathway cell-cell signaling determination of left/right symmetry compartment pattern specification nervous system development regulation of blood pressure positive regulation of cell proliferation negative regulation of cell proliferation auditory receptor cell fate commitment proximal/distal pattern formation positive regulation of gene expression astrocyte development regulation of somitogenesis spinal cord development cerebellar molecular layer formation cerebellar Purkinje cell layer structural organization regulation of cell adhesion negative regulation of epithelial cell differentiation regulation of vascular endothelial growth factor receptor signaling pathway negative regulation of interleukin-10 production negative regulation of glial cell apoptotic process organ growth regulation of growth cell fate commitment negative regulation of cell differentiation negative regulation of epidermal cell differentiation negative regulation of auditory receptor cell differentiation negative regulation of myeloid cell differentiation negative regulation of myoblast differentiation negative regulation of neuron differentiation negative regulation of Notch signaling pathway positive regulation of Notch signaling pathway positive regulation of endocytosis positive regulation of transcription from RNA polymerase II promoter lateral inhibition skeletal muscle tissue growth regulation of skeletal muscle tissue growth positive regulation of skeletal muscle tissue growth neuron fate specification inner ear development regulation of neurogenesis regulation of cell division retina development in camera-type eye retina morphogenesis in camera-type eye Notch signaling pathway involved in arterial endothelial cell fate commitment left/right axis specification nephron development proximal tubule development loop of Henle development clathrin-mediated endocytosis energy homeostasis endothelial tip cell fate specification neuronal stem cell population maintenance skin epidermis development regulation of vascular endothelial growth factor signaling pathway positive regulation of sprouting angiogenesis negative regulation of cardiac muscle cell differentiation hemopoiesis cell differentiation in utero embryonic development vasculature development epithelial cell development regionalization endothelium development embryo development ending in birth or egg hatching organ morphogenesis neuron differentiation inner ear morphogenesis odontogenesis of dentin-containing tooth auditory receptor cell differentiation eye morphogenesis embryonic morphogenesis regulation of developmental growth multicellular organismal homeostasis regulation of transport negative regulation of developmental process negative regulation of multicellular organismal process epithelial tube morphogenesis renal tubule development
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