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Invitrogen

DLL1 Polyclonal Antibody

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DLL1 Polyclonal Antibody

Product Details

PA5-80554

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-

ELISA (ELISA)

1:5,000-1:10,000
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human DLL1 protein (Met1-Gly540)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

5 mg/mL

Amount

500 µg

Purification

Protein A

Storage buffer

PBS

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2787855

Product Specific Information

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).

This antibody has specificity for Human DLL1/Delta-1.

Target Information

Delta-like protein 1 (DLL1) is a transmembrane protein characterized by epidermal growth factor (EGF)-like repeats. It is a ligand for Notch receptor. It blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Delta-like protein 1; Delta1; Drosophila Delta homolog 1; epididymis secretory sperm binding protein; H-Delta-1; Notch ligand; OTTHUMP00000017690; unnamed protein product

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Gene Aliases: Delta; DELTA1; DL1; DLL1; NEDBAS; UNQ146/PRO172

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UniProt ID: (Human) O00548

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Entrez Gene ID: (Human) 28514

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Function(s)
Notch binding calcium ion binding protein binding Tat protein binding receptor agonist activity scaffold protein binding
Process(es)
cell fate determination somitogenesis somite specification heart looping inhibition of neuroepithelial cell differentiation marginal zone B cell differentiation type B pancreatic cell development cell communication Notch signaling pathway cell-cell signaling determination of left/right symmetry compartment pattern specification regulation of blood pressure positive regulation of cell proliferation negative regulation of cell proliferation proximal/distal pattern formation positive regulation of gene expression astrocyte development regulation of somitogenesis spinal cord development cerebellar molecular layer formation cerebellar Purkinje cell layer structural organization hemopoiesis myeloid cell differentiation cell differentiation regulation of cell adhesion neuron differentiation negative regulation of epithelial cell differentiation regulation of vascular endothelial growth factor receptor signaling pathway negative regulation of interleukin-10 production negative regulation of glial cell apoptotic process organ growth regulation of growth auditory receptor cell differentiation negative regulation of cell differentiation negative regulation of epidermal cell differentiation negative regulation of auditory receptor cell differentiation negative regulation of myeloid cell differentiation negative regulation of myoblast differentiation negative regulation of neuron differentiation negative regulation of Notch signaling pathway positive regulation of Notch signaling pathway positive regulation of endocytosis positive regulation of transcription from RNA polymerase II promoter lateral inhibition skeletal muscle tissue growth regulation of skeletal muscle tissue growth positive regulation of skeletal muscle tissue growth neuron fate specification inner ear development regulation of neurogenesis regulation of cell division retina development in camera-type eye retina morphogenesis in camera-type eye neuroepithelial cell differentiation Notch signaling pathway involved in arterial endothelial cell fate commitment left/right axis specification nephron development proximal tubule development loop of Henle development clathrin-mediated endocytosis energy homeostasis endothelial tip cell fate specification neuronal stem cell population maintenance skin epidermis development regulation of vascular endothelial growth factor signaling pathway positive regulation of sprouting angiogenesis negative regulation of cardiac muscle cell differentiation
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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