|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide (DDGSREAMNNLSDFQKD (aa561 - 577)) of DLL4 protein.|
|Storage buffer||PBS with 0.05% BSA|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||3-6 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Delta-like protein 4 is a single pass type 1 transmembrane protein which plays an important role in the Notch signaling pathway by activating Notch-1 and Notch-4. DLL-4 contains a signal sequence, a DSL domain, eight epidermal growth factor-like repeats, a transmembrane domain, and an intracellular region, all of which are characteristics of members of the Delta protein family. It is essential for angiogenesis during embryonic vascular development and is involved in tumour angiogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.