Search
Proteintech
DLX2 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
26244-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DLX2 Fusion Protein Ag24663 (240-328 aa encoded by BC032558)
Conjugate
Form
Liquid
Concentration
0.35 mg/mL
Amount
52.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: SWDFGVPQR MAGGGGPGSG GSGAGSSGSS PSSAASAFLG NYPWYHQTSG SASHLQATAP LLHPTQTPQP HHHHHHHGGG GAPVSAGTIF (240-328 aa encoded by BC032558)
Target Information
Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: DII A; distal-less homeo box 2; Homeobox protein DLX-2; Homeobox protein TES-1; unnamed protein product
Gene Aliases: AW121999; Dlx-2; DLX2; TES-1; TES1
UniProt ID: (Human) Q07687, (Mouse) P40764
Entrez Gene ID: (Human) 1746, (Mouse) 13392
transcription regulatory region sequence-specific DNA binding
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
single-stranded RNA binding
protein binding
sequence-specific double-stranded DNA binding
sequence-specific DNA binding
homeodomain transcription factor
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
Notch signaling pathway
brain development
proximal/distal pattern formation
neuroblast differentiation
subpallium development
hippocampus development
olfactory bulb development
forebrain neuron differentiation
cerebral cortex GABAergic interneuron differentiation
cerebral cortex GABAergic interneuron fate commitment
cell differentiation
odontogenesis of dentin-containing tooth
positive regulation of cell differentiation
negative regulation of Notch signaling pathway
positive regulation of transcription from RNA polymerase II promoter
negative regulation of photoreceptor cell differentiation
embryonic cranial skeleton morphogenesis
embryonic skeletal system development
oligodendrocyte differentiation
negative regulation of oligodendrocyte differentiation
branching morphogenesis of a nerve
cartilage development
GABAergic neuron differentiation
positive regulation of amacrine cell differentiation
transcription from RNA polymerase II promoter
multicellular organism development
regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support