Peptide sequence: MTGVFDSLVA DMHSTQIAAS STYHQHQQPP SGGGAGPGGN SSSSSSLHKP
Sequence homology: Cow: 87%; Dog: 92%; Guinea Pig: 100%; Horse: 86%; Human: 100%; Mouse: 92%
Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 2.
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Protein Aliases: DII A; distal-less homeo box 2; Distal-less homeobox 2; Homeobox protein DLX-2; Homeobox protein TES-1; TES-1; TES1
Gene Aliases: AW121999; BOS_1710; Dlx-2; DLX2; TES-1; TES1