Peptide sequence: MTGVFDRRVP SIRSGDFQAP FQTSAAMHHP SQESPTLPES SATDSDYYSP
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%
This gene encodes a member of a homeobox transcription factor gene family similar to the Drosophila distal-less gene. The encoded protein may play a role in bone development and fracture healing. Mutation in this gene, which is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 7, may be associated with split-hand/split-foot malformation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: distal-less homeo box 5; Distal-less homeobox 5; distal-less homeobox protein 5; DLX-3; Homeobox protein DLX-3; Homeobox protein DLX-5; RDLX; SHFM1D; split hand/foot malformation type 1 with sensorineural hearing loss
Gene Aliases: AI385752; BOS_4014; DLX5; RDLX; SHFM1D