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Proteintech
DMGDH Polyclonal Antibody
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Product Details
24813-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DMGDH Fusion Protein Ag20529 (284-613 aa encoded by BC022388)
Conjugate
Form
Liquid
Concentration
0.34 mg/mL
Amount
51 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: ARESYGFNN IVGYPKEERF AGRPTQRVSG LYQRLESKCS MGFHAGWEQP HWFYKPGQDT QYRPSFRRTN WFEPVGSEYK QVMQRVAVTD LSPFGKFNIK GQDSIRLLDH LFANVIPKVG FTNISHMLTP KGRVYAELTV SHQSPGEFLL ITGSGSELHD LRWIEEEAVK GGYDVEIKNI TDELGVLGVA GPQARKVLQK LTSEDLSDDV FKFLQTKSLK VSNIPVTAIR ISYTGELGWE LYHRREDSVA LYDAIMNAGQ EEGIDNFGTY AMNALRLEKA FRAWGLEMNC DTNPLEAGLE YFVKLNKDQN SCFAHFKEEN GWVSRWAIRP Y (284-613 aa encoded by BC022388)
Target Information
This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Dimethylglycine dehydrogenase, mitochondrial; EC 1.5.99.2; M2GD; ME2GLYDH; unnamed protein product
Gene Aliases: 1200014D15Rik; AI787269; DMGDH; DMGDHD; ME2GLYDH
UniProt ID: (Human) Q9UI17, (Mouse) Q9DBT9
Entrez Gene ID: (Human) 29958, (Mouse) 74129, (Rat) 245961
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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