This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Immunogen sequence: LAADSASGEV GNPLGGSPVK NSLRGLPGPY VPGQTGNQWQ MKNMENRHAM SSQYRMHSYY PPPSYLGQSV PQFFTFEDAP SYPEARASVF SPPSSQDSGL VSLSSSSPIS NKSTKAVLEC EPASEPSSFT VTPVI
Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 78%.
This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DM domain expressed in testis 1; DM domain expressed in testis protein 1; Doublesex- and mab-3-related transcription factor 1
Gene Aliases: CT154; DMRT1; DMT1
UniProt ID: (Human) Q9Y5R6
Entrez Gene ID: (Human) 1761
Molecular Function: DNA-binding transcription factor