Proteintech

DNAH17 Polyclonal Antibody

DNAH17 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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DNAH17 Antibody (24488-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human kidney tissue slide using 24488-1-AP ( DNAH17 Antibody) at dilution of 1:50 (under 40x lens).

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Product Details

24488-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

View 5 publications 5 publications

Product Specifications

Species Reactivity

Human

Published species

Not Applicable

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

DNAH17 Fusion Protein Ag20033 (299-644 aa encoded by BC112284)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.43 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MEQADFTML PTFIAKVLDT ICFIWATSEY YNTPARIIVI LQEFCNQIIE MTRTFLSPEE VLKGLQGEIE EVLSGISLAV NVLKELYQTY DFCCVNMKLF FKDKEPVPWE FPSSLAFSRI NSFFQRIQTI EELYKTAIEF LKLEKIELGG VRGNLLGSLV TRIYDEVFEL VKVFADCKYD PLDPGDSNFD RDYADFEIKI QDLDRRLATI FCQGFDDCSC IKSSAKLLYM CGGLMERPLI LAEVAPRYSV MLELFDAELD NAKILYDAQM AASEEGNIPL IHKNMPPVAG QLKWSLELQE RLEVSMKHLK HVEHPVMSGA EAKLTYQKYD EMMELLRCHR EKIYQQW (299-644 aa encoded by BC112284 )

Target Information

Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. DNAH17 is a heavy chain associated with axonemal dynein (Milisav and Affara, 1998 [PubMed 9545504]).[supplied by OMIM, Mar 2008].

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Population-based genetic analysis in infertile men reveals novel mutations of ADAD family members in patients with impaired spermatogenesis.

Human molecular genetics

Dai S,Liu M,Liu M,Jiang C,Yang Y,Han H,Yang Y,Jiang X,Shen Y

Thu May 18 00:00:00 UTC 2023

Microcystin leucine arginine induces human sperm damage: Involvement of the Ca²⁺/CaMKKβ/AMPK pathway.

Ecotoxicology and environmental safety

Guo X,Meng R,Liu J,Zhang S,Liu H,Du X,Zhang H,Li Y

Mon May 01 00:00:00 UTC 2023

A novel mutation in DNAH17 is present in a patient with multiple morphological abnormalities of the flagella.

Reproductive biomedicine online

Zheng R,Sun Y,Jiang C,Chen D,Yang Y,Shen Y

Wed Sep 01 00:00:00 UTC 2021

The effect of a novel LRRC6 mutation on the flagellar ultrastructure in a primary ciliary dyskinesia patient.

Journal of assisted reproduction and genetics

Li Y,Jiang C,Zhang X,Liu M,Sun Y,Yang Y,Shen Y

Mon Mar 01 00:00:00 UTC 2021

DNAH17 is associated with asthenozoospermia and multiple morphological abnormalities of sperm flagella.

Annals of human genetics

Sha Y,Wei X,Ding L,Mei L,Huang X,Lin S,Su Z,Kong L,Zhang Y,Ji Z

Fri May 01 00:00:00 UTC 2020

DNAH17 is associated with asthenozoospermia and multiple morphological abnormalities of sperm flagella.

Annals of human genetics

Sha Y,Wei X,Ding L,Mei L,Huang X,Lin S,Su Z,Kong L,Zhang Y,Ji Z

Fri May 01 00:00:00 UTC 2020

Loss-of-function mutation in DNAH8 induces asthenoteratospermia associated with multiple morphological abnormalities of the sperm flagella.

Clinical genetics

Yang Y,Jiang C,Zhang X,Liu X,Li J,Qiao X,Liu H,Shen Y

Thu Oct 01 00:00:00 UTC 2020

Bioinformatics

Protein Aliases: Axonemal beta dynein heavy chain 17; axonemal dynein heavy chain; Axonemal dynein heavy chain-like protein 1; Ciliary dynein heavy chain 17; Ciliary dynein heavy chain-like protein 1; Dynein axonemal heavy chain 17; Dynein axonemal light chain 2; dynein light chain 2, axonemal; dynein, axonemal, heavy chain 17; dynein, axonemal, heavy chain like 1; dynein, axonemal, heavy like 1; dynein, axonemal, heavy polypeptide 17; FLJ40457

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Gene Aliases: DNAH17; DNAHL1; DNEL2

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UniProt ID: (Human) Q9UFH2

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Entrez Gene ID: (Human) 8632

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Function(s)

microtubule motor activity ATP binding ATPase activity microtubule binding motor protein

Process(es)

cilium or flagellum-dependent cell motility microtubule-based movement

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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DNAH17 Polyclonal Antibody

DNAH17 Antibody (24488-1-AP) in IHC (P)

Product Details

24488-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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