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Proteintech
DNAH5 Polyclonal Antibody
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Product Details
31079-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DNAH5 fusion protein Ag34647
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Amount
45 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: LNKTEVEDAI LEGNQIERID QLFAVGGLRH LMFYYQDVEE AETGQLGSLG GVNLVSGKIK KPKVFVTEGN DVALTGVCVF FIRTDPSKAI TPDNIHQEVS F
Target Information
This gene encodes a dynein protein, which is part of a microtubule-associated motor protein complex consisting of heavy, light, and intermediate chains. This protein is an axonemal heavy chain dynein. It functions as a force-generating protein with ATPase activity, whereby the release of ADP is thought to produce the force-producing power stroke. Mutations in this gene cause primary ciliary dyskinesia type 3, as well as Kartagener syndrome, which are both diseases due to ciliary defects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Axonemal beta dynein heavy chain 5; axonemal dynein heavy chain 5; Ciliary dynein heavy chain 5; Dynein axonemal heavy chain 5; dynein heavy chain 5, axonemal; dynein, axon, heavy chain 5; dynein, axonemal, heavy polypeptide 5; mDNAH5; unnamed protein product
Gene Aliases: AU022615; b2b1134Clo; b2b1154Clo; b2b1537Clo; b2b1565Clo; b2b601Clo; CILD3; DNAH5; DNAHC5; HL1; KIAA1603; KTGNR; Mdnah5; mKIAA1603; PCD
UniProt ID: (Human) Q8TE73, (Mouse) Q8VHE6
Entrez Gene ID: (Human) 1767, (Mouse) 110082
cilium movement
microtubule-based movement
determination of left/right symmetry
lateral ventricle development
sperm motility
outer dynein arm assembly
left/right axis specification
epithelial cilium movement
heart development
establishment of localization in cell
cilium morphogenesis
cilium movement involved in cell motility
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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