Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Raji.
Predicted reactivity: Mouse (99%), Rat (99%), Zebrafish (84%), Xenopus laevis (90%), Chicken (94%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain. The product of this gene works as a cochaperone of Hsp70s in protein folding and mitochondrial protein import in vitro.
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Protein Aliases: cell cycle progression 3 protein; Cell cycle progression restoration gene 3 protein; CPR3; DJ3; DJA2; DNAJ; DnaJ (Hsp40) homolog, subfamily A, member 2; DnaJ homolog subfamily A member 2; DNJ3; HIRA interacting protein 4; HIRA-interacting protein 4; HIRIP4; PRO3015; RDJ2; Renal carcinoma antigen NY-REN-14
Gene Aliases: CPR3; DJ3; DJA2; DNAJ; DNAJA2; DNJ3; HIRIP4; PRO3015; RDJ2
UniProt ID: (Human) O60884
Entrez Gene ID: (Human) 10294